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Suboxone is a prescription medication containing buprenorphine and naloxone, used to treat opioid dependence. It helps reduce withdrawal symptoms and cravings in individuals undergoing recovery from opioid addiction. How Suboxone Works Buprenorphine: A partial opioid agonist that reduces cravings and withdrawal symptoms. Naloxone: An opioid antagonist that prevents misuse by injection. The combination allows patients to stabilize safely while participating in counseling and recovery programs.